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Featured Articles

  • April 10, 2018

    81 Percent of Obese Americans Experience Foot Pain

    An astounding 81 percent of obese Americans say they suffer from foot pain and at times experience multiple foot and ankle conditions, according to a recent survey by the American Podiatric Medical Association (APMA). The study surveyed 1,275 US adults, ages 18 and older, to gain information about how many overweight and obese Americans experience foot pain. Read More

    Lower Leg Lymphedema Common After Gyn Surgery

    Approximately 20-40% of women have significant lower-extremity lymphedema after surgery for gynecologic cancer, according to data from the most comprehensive study of the issue to date. The incidence of lymphedema ranged from 18% after surgery for endometrial cancer to 40% in women who had surgery for vulvar cancer. Lymphedema appeared within 6 to 12 weeks after surgery in a majority of cases but had delayed onset of up to 18 months in some cases. Use of a multifactor definition helped distinguish true lower-extremity lymphedema from an increase in leg volume. Read More

    Could less Restrictive Diets in Elderly Patients Improve Health Outcomes?

    Widening food choices in older adults in long-term and post-acute care (PAC) settings may reduce malnutrition and improve quality of life, suggests U.S. industry body. While respecting the need to follow established dietary guidelines for specific medical conditions, the authors suggest that restrictions should be loosened if a patient's oral intake is poor. Care providers should examine the trade-off between the consequences of malnutrition and unintended weight loss (UWL) versus specific disease-related health risks. Read More

    Compression Stockings: How to Choose and Use Them

    Compressions stockings are often the first line of defense when treating varicose veins, but they are used to treat many conditions. Graduated compression stockings assist with proper circulation. The compression is strongest at the ankle and gradually decreases toward the top of the stocking. The additional pressure will keep blood from pooling in the legs and reduce swelling. Read More

  • April 3, 2018

    Nanofiber Dressings Accelerate Healing

    A new wound dressing that can accelerate healing and improve tissue regeneration has been developed by researchers which draws inspiration from animals and plants to restore tissue. Two different types of nanofiber dressing have been developed using naturally occurring proteins from animals and plants to regrow tissue and promote healing by researchers at Wyss Institute for Biologically Inspired Engineering Harvard John A. Paulson SEAS, as published separately in Biomaterials which describes wound tissue inspired by fetal tissue, and Advanced Healthcare Materials which describes soy based nanofibers that promotes and enhances wound healing. Read More

    Failure To Save A Child In Wartime Inspires Wound-Healing Tech

    "I couldn't save that kid," he says. "But that doesn't mean there's not something I could do." So Parker assembled a team of young scientists. Their job: Find a better way to heal burns and other wounds. The team focused on a discovery made in the late 1970s and early 1980s, when surgeons began correcting birth defects in babies still in the womb. After these babies were born, doctors took a close look at the sites where incisions had been made. "And they realized that they typically healed with a lot less [scarring] or, in some cases, without any scars at all." Read More

    Set Clear Rules to Stop bad Behavior That Worsens Morale

    Yelling. Screaming. Swearing. Angry outbursts. Negative or demeaning comments about patients, physicians or other health professionals. These are all examples of disruptive behavior that can impede high-quality care and contribute to low morale in health care organizations. And they may also be a manifestation of physician burnout and a signal that systemic change to restore joy in practice is needed. Read More

    Harvard’s New Skin-Style Bandages Heal Wounds at an Accelerated Rate

    A team of researchers at Harvard University have developed two novel nanofiber wound dressings which are able to rapidly accelerate the healing process, as well as improve tissue regeneration. Described in separate academic papers, the new bandages use proteins which are found naturally occurring in plants and animals to promote enhanced healing. “In these papers, two novel fibrous materials were developed and specifically tailored to applications in the field of regenerative medicine, one was produced from soy protein that contains several human peptide analogs, critical in regulating wound closure, while the other was manufactured from a protein called fibronectin that is believed to play a crucial role in regeneration.” Read More

  • March 27, 2018

    Modified Biomaterials Self-Assemble on Temperature Cues

    Biomedical engineers have demonstrated a new approach to making self-assembled biomaterials that relies on protein modifications and temperature. The hybrid approach allows researchers to control self-assembly more precisely, which may prove useful for a variety of biomedical applications, from drug delivery to wound-healing. Read More

    How Rounding is Helping Hospitals Reduce Patient Readmissions

    Hospital readmission rates are declining and there are several contributing factors. One of the main factors is that reducing patient admissions within 30 days after being discharged from an earlier hospital stay, whether the patient is admitted at the same or a different hospital, or for a different reason, has been a tremendous focus with the implementation of the Hospital Readmission Reduction Program (HRRP). A provision in the Affordable Care Act established the HRRP, which requires the Centers for Medicare and Medicaid Services to reduce payments to Inpatient Prospective Payment System hospitals with excess readmissions in October 2012. Facing penalties and reimbursement reductions, hospitals have taken a proactive approach to ensuring readmissions are minimized. Read More

    Nanofiber Dressings Promote Skin Regeneration and Wound Healing

    As one of the largest segments of the population move into their six and seventh decades, advanced healthcare initiatives focused on wound healing are imperative to improve quality of life and help keep seniors active. Now, investigators from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and the Wyss Institute for Biologically Inspired Engineering have developed new wound dressings that dramatically accelerate healing and improve tissue regeneration. The researchers found that naturally occurring proteins in plants and animals can promote healing and regrow tissue. Read More

    Four of the Most Life-Threatening Skin Conditions and What you Should Know About Them

    Dermatological emergencies are uncommon, but can cause devastating complications and death if not recognised and treated early. Some skin conditions require treatment in an intensive care unit. Here are some of the most serious skin conditions and what you should know about recognising them.  Read More

  • March 20, 2018

    Harlequin Ichthyosis Congenital Skin Condition

    Harlequin Ichthyosis is a rare, congenital skin condition. It affects the skin over almost the whole body of an infant, and carries a high risk of neonatal death due to severe and life-threatening infection. The incidence of the condition is about one in every 500,000 people. Both males and females are affected equally. The disease is caused by a mutation of the ABCA12 gene. This gene helps to direct the production of the ABCA12 protein involved in transporting fats within the epidermis, which is essential for normal skin synthesis. Read More

    Systemic Conditions That can Affect Skin

    It is important to remember that the skin can act as a window to a patient’s general health and that changes in the skin can signal underlying disease.A physician writing in the journal Medicine, says it is incumbent upon dermatologists to conduct a thorough examination of the skin, nails, mucosal surfaces, and hair so as to not overlook clues that might help arrive at a diagnosis of a systemic condition. A consultant dermatologist at St. George’s NHS University Hospital Trust in London, outlines systemic conditions that can affect the skin. Dr. Lamb stresses that by looking at the skin and noticing any changes in the skin, clinicians can potentially identify a condition that has remained undiagnosed.  Read More

    Call to Empower Care Staff in Monitoring Skin Integrity

    Care workers are critical to preventing wounds among aged care residents and they need to be empowered to act, says an aged care wounds specialist. The usual strategy in aged care is to have care workers provide the basics, such as showering or assisting with meals, but they have a key role to play in wound prevention, said Hayley Puckeridge, Uniting wound clinical nurse consultant. She called on aged care organizations to empower their care staff because they are critical to observing skin integrity issues as they saw residents at their most vulnerable including when naked. Read More

    Drawing Inspiration from Plants and Animals to Restore Tissue

    Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and the Wyss Institute for Biologically Inspired Engineering have developed new wound dressings that dramatically accelerate healing and improve tissue regeneration. The two different types of nanofiber dressings, described in separate papers, use naturally-occurring proteins in plants and animals to promote healing and regrow tissue. The most recent paper, published in Biomaterials, describes a wound dressing inspired by fetal tissue.  Read More

  • March 13, 2018

    Should Prophylactic Antibiotic Therapy be Used to Prevent Recurrent Infection in Patients with Lymphedema?

    In one study, 28% of people with cancer-related lymphedema experienced cellulitis, a common complication of all types of lymphedema. In some patients, cellulitis can result in sepsis and the need for high-dependency hospital care. People with lymphedema may experience recurrent episodes of cellulitis. These can cause further damage to the lymphatic system resulting in worsening lymphedema. This, in turn, leads to an increased risk for further cellulitis. So, a vicious circle may develop.  Read More

    Decreased Health-Related Quality of Life in Patients With Diabetic Foot Problems

    The aim of this study was to investigate health-related quality of life (HRQoL) in patients with diabetic foot problems and compare the HRQoL between diabetic patients with: 1) diabetic foot problems (DF), including diabetic foot ulcer (DFU) or amputation (AMPU); 2) other diabetic complications (COM), such as diabetic retinopathy (DR), end-stage renal disease (ESRD), or coronary artery disease (CAD); and 3) no diabetic complication (CON).  Read More

    Critical Limb Ischemia Treatment Shows no Improvement at Three Months

    Patients with foot ulcers or gangrene who received the experimental drug JVS-100 did not show evidence of faster wound healing, compared with those receiving a placebo, in a study presented at the American College of Cardiology's 67th Annual Scientific Session. The study focused on patients with a condition known as critical limb ischemia, which occurs when the arteries that supply blood to the limbs (typically the legs) become stiffened or blocked. A lack of adequate blood flow to the extremities can lead to painful skin lesions or gangrene sores that persist for months or years. Read More

    Pioneering Treatments for Healing Chronic Wounds

    Chronic wounds differ from normal acute wounds, because they do not go through the normal healing process of inflammation, proliferation, and remodelling; instead they stop at the inflammation stage, and the healing process is stopped completely. It is estimated that 1-2% of the population in developed countries will experience a chronic wound during their lifetime. In the US alone, there are over six million chronic wound patients, and treatment is costing around $25 billion per year. However there has been many important breakthroughs recently in the field of treating chronic wounds. Read More

  • March 6, 2018

    Smart Bandage, Smartphone Controlled

    Even with medical science advances, the treatment of wounds is often fairly low tech. The process of changing bandages and applying the right medication at the right interval is often labor intensive. Promoting faster healing and preventing infection remain concerns. Scientists at the University of Nebraska-Lincoln, Harvard Medical School and MIT have developed a bandage that works with a smartphone to dispense the right medication onto the wound at the right time. The smart bandage features electrically conductive fibers coated in a hydrogel that contains medicines like painkillers, antibiotics and tissue-regenerating therapies, which can target a specific type of wound. Read More

    Successful Treatment of CLI Requires Collaboration, Awareness

    Patients with critical limb ischemia face enormous challenges, and the medical community must work closely together to improve their lives via the best known treatments, a speaker said at the International Symposium on Endovascular Therapy (ISET). “We make decisions about the treatments for these patients without even thinking about which ones necessarily work best and last the longest, but our patients are begging us to figure this out.” Read More

    Preventing a Million Diabetic Foot Amputations

    Every 20 seconds someone, somewhere on the planet, loses a foot due to diabetes. Foot ulcers are the starting point of more than 80% of these amputations, and they could be prevented. The number of people diagnosed with diabetes, globally, has risen from 108m in 1980 to 422m in 2014. This is a huge burden on healthcare services as diabetes is associated with many long-term health complications, including peripheral neuropathy, where nerves become damaged, leading to pain, numbness or weakness. While costs are increasing, healthcare professionals have yet to find an effective way to screen diabetic patients and treat complications caused by the disease. Read More

    A Bacterium That Attacks Burn Victims will Soon be Unarmed

    The bacterium Pseudomonas aeruginosa is amongst the main causes of infections and sepsis in people suffering from severe burns. Researchers have succeeded in revealing the dynamics of the pathogen's physiology and metabolism during its growth in exudates, the biological fluids that seep out of burn wounds. This study allows to follow the strategies developed by Pseudomonas aeruginosa to proliferate and, thus, to guide the development of innovative treatments. Read More