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Lymphedema, an adverse effect of breast cancer treatment that causes swelling in the arms or legs, occurs in more than 41% of patients within 10 years of their surgery. According to a new study published in mHealth, researchers have developed an efficient way to detect lymphedema with machine learning, a type of artificial intelligence. Lymphedema can be a debilitating adverse effect of breast cancer treatment that can progress to a severe and chronic condition if left untreated. There is no cure for lymphedema, but early detection and treatment can help reduce symptoms and keep it from worsening. Read More
For open traumatic wounds involving fracture or soft tissue, there is "no clear difference" between standard care and negative pressure wound therapy (NPWT), and the latter is unlikely to be cost-effective, according to a recent Cochrane Review. Four studies on open-fracture wounds found no clear difference between NPWT and standard care. After pooling data on wound infection from four studies of 596 participants with an average follow-up of 30 days, the authors concluded, "It is uncertain whether NPWT at 125 mmHg reduces the risk of wound infection (in open-fracture wounds) compared with standard care (RR, 0.48)," with very low-certainty evidence. Read More
Specific immune cells have the ability to produce a healing factor that can promote wound repair in the intestine, a finding that could lead to new, potential therapeutic treatments for inflammatory bowel disease (IBD), according to a new research study. The research team, led by Georgia State University and the University of Michigan, wanted to understand how a wound heals in the intestine because in IBD, which includes Crohn's disease and ulcerative colitis, damage to the intestinal epithelial barrier allows bacteria in the intestine to go across the barrier and stimulate the body's immune system. Read More
Researchers from Sweden and India have come up with yet another novel use for spider silk’s unusual mix of strength and elasticity: Creating artificial skin and wound dressings for helping heal wounds. “We have developed two types of silk-based constructs: Nanofibrous matrices which serve as bioactive wound dressings, and microporous sponges cultured with human skin cells to serve as artificial skin. Read More